Journal article
Grandmaternal smoking increases asthma risk in grandchildren: A nationwide Swedish cohort
CJ Lodge, L Bråbäck, AJ Lowe, SC Dharmage, D Olsson, B Forsberg
Clinical and Experimental Allergy | WILEY | Published : 2018
DOI: 10.1111/cea.13031
Abstract
Background: There is growing interest in exposures prior to conception as possible risk factors for offspring asthma. Although partially supported by evidence from limited human studies, current evidence is inconsistent and based on recall of exposure status. Objective: We aimed to investigate grandmaternal smoking during pregnancy and the risk of asthma in grandchildren using prospectively collected population-based data. Methods: Information on grandmaternal and maternal smoking during pregnancy and grandchild use of asthma medications was collected from national Swedish registries. Associations between grandmaternal smoking during pregnancy (10-12 weeks) and asthma medication use in grand..
View full abstractGrants
Funding Acknowledgements
This project was supported by the Medical Faculty at Umea University and the Swedish Research Council through the Swedish Initiative for Research on Microdata in the Social And Medical Sciences (SIMSAM) network grant. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. AL and SD were funded from NHMRC fellowships. CL was also funded from a Lillian Roxon travel grant through Asthma Australia. The corresponding author (CL) had full access to all the data in the study and the final responsibility for the decision to submit for publication