Tailored and Adaptive Computerized Cognitive Training in Older Adults at Risk for Dementia: A Randomized Controlled Trial

Abstract

Background: Computerized CognitiveTraining (CCT) has been shownto improve cognitive function in older adults with mild cognitive impairment (MCI) or mood-related neuropsychiatric symptoms (MrNPS), but many questions remain unresolved. Objective: To evaluate the extent to which CCT benefits older adults with both MCI and MrNPS, and its effects on metacognitive and non-cognitive outcomes, as well as establish whether adapting difficulty levels and tailoring to individuals' profile is superior to generic training. Method: Older adults with MCI (n = 9), MrNPS (θ = 11), or both (MCI+, θ = 25) were randomized into a home-based individually-Tailored and adaptive CCT (θ = 21) or an active control co..