Extubation Failure Is Associated with Increased Mortality Following First Stage Single Ventricle Reconstruction Operation

Abstract

Objectives: To identify the prevalence, causes, risk factors, and outcomes associated with extubation failure following first stage single ventricle reconstruction surgery. Design: Retrospective cohort analysis of neonates who underwent a first stage single ventricle reconstruction operation. Extubation failure was defined as endotracheal reintubation within 48 hours of first extubation attempt. Setting: The Royal Children's Hospital, Melbourne. Patients: Data were collected for all infants who underwent a Norwood or Damus-Kaye-Stansel procedure between 2005 and 2014 at our institution. Interventions: None. Measurements and Main Results: Extubation failure occurred in 23 of 137 neonates (16...