Journal article

A comparative assessment by optical coherence tomography of the performance of the first and second generation of the everolimus-eluting bioresorbable vascular scaffolds.

Josep Gomez-Lara, Salvatore Brugaletta, Roberto Diletti, Scot Garg, Yoshinobu Onuma, Bill D Gogas, Robert Jan van Geuns, Cécile Dorange, Susan Veldhof, Richard Rapoza, Robert Whitbourn, Stephan Windecker, Hector M Garcia-Garcia, Evelyn Regar, Patrick W Serruys

European Heart Journal | Published : 2011


AIMS: The first generation of the everolimus-eluting bioresorbable vascular scaffold (BVS 1.0) showed an angiographic late loss higher than the metallic everolimus-eluting stent Xience V due to scaffold shrinkage. The new generation (BVS 1.1) presents a different design and manufacturing process than the BVS 1.0. This study sought to evaluate the differences in late shrinkage, neointimal response, and bioresorption process between these two scaffold generations using optical coherence tomography (OCT). METHODS AND RESULTS: A total of 12 lesions treated with the BVS 1.0 and 12 selected lesions treated with the revised BVS 1.1 were imaged at baseline and 6-month follow-up with OCT. Late shrink..

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