Trends and Impact of Door-to-Balloon Time on Clinical Outcomes in Patients Aged <75, 75 to 84, and ≥85 Years With ST-Elevation Myocardial Infarction

M Yudi; G Hamilton; O Farouque; N Andrianopoulos; SJ Duffy; J Lefkovits; A Brennan; D Fernando; C Hiew; M Freeman; C Reid; R Dakis; AE Ajani; DJ Clark; JA Shaw; A Walton; A Dart; A Broughton; J Federman; C Keighley; C Hengel; KH Peter; D Stub; W Chan; J O'Brien; L Selkrig; K Rankin; R Vandernet; R Huntington; S Pally; M Horrigan; J Johns; L Oliver; J Brennan; R Chan; G Proimos; T Dortimer; B Chan; V Nadurata; R Huq; A Al-Fiadh; H Sugumar; J Ramchand; H Han; S Picardo; L Brown; E Oqueli; A Sharma; B Zhu; N Ryan; T Harrison; G New; L Roberts; M Rowe; Y Cheong; C Goods; A Teh; S Parfrey; J Ramzy; A Koshy; P Venkataraman; D Flannery; M Sebastian; T Yip; M Mok; C Jaworski; A Hutchinson; C Cimenkaya; P Ngu; B Khialani; H Salehi; M Turner; J Dyson; B McDonald; D Van Den Nouwelant; K Halliburton; H Krum; V Chand; D Dinh; BP Yan; R Warren; D Eccleston; R Iyer; R Gurvitch; W Wilson; M Brooks; S Biswas; J Yeoh

Journal article

Trends and Impact of Door-to-Balloon Time on Clinical Outcomes in Patients Aged <75, 75 to 84, and ≥85 Years With ST-Elevation Myocardial Infarction

M Yudi, G Hamilton, O Farouque, N Andrianopoulos, SJ Duffy, J Lefkovits, A Brennan, D Fernando, C Hiew, M Freeman, C Reid, R Dakis, AE Ajani, DJ Clark, JA Shaw, A Walton, A Dart, A Broughton, J Federman, C Keighley Show all

American Journal of Cardiology | EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC | Published : 2017

DOI: 10.1016/j.amjcard.2017.07.005

Abstract

Guidelines strongly recommend patients with ST-elevation myocardial infarction (STEMI) receive timely mechanical reperfusion, defined as door-to-balloon time (DTBT) ≤90 minutes. The impact of timely reperfusion on clinical outcomes in patients aged 75–84 and ≥85 years is uncertain. We analysed 2,972 consecutive STEMI patients who underwent primary percutaneous coronary intervention from the Melbourne Interventional Group Registry (2005–2014). Patients aged <75 years were included in the younger group, those aged 75–84 years were in the elderly group and those ≥85 years were in the very elderly group. The primary endpoints were 12-month mortality and major adverse cardiovascular events (MACE)..

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University of Melbourne Researchers

Omar Farouque Author

David Clark Author

Karlheinz Peter Author

William Chan Author

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Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

The Melbourne Interventional Group acknowledges unrestricted educational grant funding from Abbott Vascular, Astra-Zeneca, Medtronic, MSD, Pfizer, Servier, and The Medicines Company. These companies do not have access to the data, and do not have the right to review manuscripts before publication. Dr. Yudi is supported by a National Health and Medical Research Council Postgraduate Scholarship (APP 1115163) and National Heart Foundation Health Professional Scholarship (Award ID 101130). Professor Duffy's and Professor Reid's work is funded by National Health and Medical Research Council of Australia Grants.