Journal article

Establishing contemporary trends in hepatitis B sero-epidemiology in an Indigenous population

J Davies, SQ Li, SY Tong, RW Baird, M Beaman, G Higgins, BC Cowie, JR Condon, JS Davis

Plos One | PUBLIC LIBRARY SCIENCE | Published : 2017

Open access

Abstract

Background: Indigenous populations globally are disproportionately affected by chronic hepatitis B virus (HBV) infection however contemporary sero-prevalence data are often absent. In the Indigenous population of the Northern Territory (NT) of Australia the unique C4 sub-genotype of HBV universally circulates. There are no studies of the sero-prevalence, nor the impact of the vaccination program (which has a serotype mismatch compared to C4), at a population-wide level. Methods: We examined all available HBV serology results obtained from the three main laboratories serving NT residents between 1991 and 2011. Data were linked with a NT government database to determine Indigenous status and t..

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Grants

Funding Acknowledgements

JD, JSD and SYT received salary support from the Australian National Health & Medical Research Council and JD also received salary support from the Sidney Myer Fund. The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. Western Diagnostic Pathology provided support in the form of salary for MB but did not have any additional role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. The specific role of this author is articulated in the author contributions section. There was no other specific funding for this project.