Journal article

Analysis of cultivable microbiota and diet intake pattern of the long-lived naked mole-rat

Tewodros Debebe, Susanne Holtze, Michaela Morhart, Thomas Bernd Hildebrandt, Steffen Rodewald, Klaus Huse, Matthias Platzer, Dereje Wyohannes, Salomon Yirga, Alemayehu Lemma, Rene Thieme, Brigitte Koenig, Gerd Birkenmeier

GUT PATHOGENS | BMC | Published : 2016

Abstract

BACKGROUND: A variety of microbial communities exist throughout the human and animal body. Genetics, environmental factors and long-term dietary habit contribute to shaping the composition of the gut microbiota. For this reason the study of the gut microbiota of a mammal exhibiting an extraordinary life span is of great importance. The naked mole-rat (Heterocephalus glaber) is a eusocial mammal known for its longevity and cancer resistance. METHODS: Here we analyzed its gut microbiota by cultivating the bacteria under aerobic and anaerobic conditions and identifying their species by mass spectrometry. RESULTS: Altogether, 29 species of microbes were identified, predominantly belonging to Fir..

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University of Melbourne Researchers

Grants

Awarded by Europaischer Sozialfond ESF


Awarded by Leibniz Association


Funding Acknowledgements

GB, RT were supported by Grants of the Europaischer Sozialfond ESF (100098250). TD was supported by Katholischer Akademischer Auslander Dienst (KAAD). TBH, SH, and MM were supported by the Leibniz Association (SAW-2012-FLI-2). The funding bodies were not involved in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript.