Early use of inhaled nedocromil sodium in children following an acute episode of asthma.
AM Edwards, J Lyons, E Weinberg, F Weinberg, JD Gillies, G Reid, CF Robertson, P Robinson, M Dalton, P Van Asperen, C Wilson, J Mullineux, A Mullineux, PD Sly, M Cox, AF Isles
Thorax | Published : 1999
BACKGROUND: Current guidelines on the treatment of childhood asthma recommend the introduction of an anti-inflammatory drug in children who have persistent symptoms and require regular treatment with a bronchodilator. The efficacy and safety of inhaled nedocromil sodium (Tilade Mint aerosol) administered using a Fisonair spacer at a dose of 4 mg three times daily was compared with placebo in the treatment of asthmatic children aged 6-12 years who are symptomatic and recovering from an acute exacerbation of asthma. METHODS: A group comparative, double blind, placebo controlled trial was performed in children who were recovering from an acute episode of asthma following treatment in the emerge..View full abstract