Survival motor neuron gene 2 silencing by DNA methylation correlates with spinal muscular atrophy disease severity and can be bypassed by histone deacetylase inhibition

Grants

Funding Acknowledgements

This work was kindly supported by the 'Initiative Forschung und Therapie fur SMA' (to E. H. and to B. W.), the 'Koln Fortune Program/Faculty of Medicine, University of Cologne' (to E. H.), the 'Deutsche Forschungsgemeinschaft (DFG)' (to E. H., to I. B. and to B. W.), the 'Wilhelm Sander Foundation' (to E. H., I.Y.E. and I. B.), the 'Families of Spinal Muscular Atrophy' (to B. W. and E. H.) and the 'Center for Molecular Medicine Cologne' (to B. W. and E. H.). The 'Monash International Post graduate Research Scholarship (MIPRS)' and the 'Monash Graduate Scholarship (MGS)' (to S. L.). Funding to pay the Open Access charge was provided by the 'Initiative Forschung und Therapie fur SMA'.