Journal article

AN OPEN EVALUATION OF MIDAZOLAM AS A HYPNOTIC

TR NORMAN, A FULTON, GD BURROWS, B DAVIES

CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL | EXCERPTA MEDICA INC | Published : 1984

Abstract

The efficacy of midazolam as a hypnotic was assessed in 25 psychiatric inpatients, 16 with mild insomnia and 9 with moderate insomnia. After a two-night placebo period, midazolam was administered for 7 consecutive nights and the dosage adjusted according to effect. No patients received more than 30 mg., with the average dose being 14.8 ± 7.2 mg. There were no significant differences in dosage requirements between mild and moderate insomnia groups (P>0.05; Chi squared). The majority of patients reported satisfactory sleep with few dreams and sleep induction time of less than 1 hour. Two tests of memory were administered each morning of the study. No significant changes from baseline values we..

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