Journal article

PLATELET MONOAMINE-OXIDASE ACTIVITY AND CIGARETTE-SMOKING

TR NORMAN, KG CHAMBERLAIN, MA FRENCH, GD BURROWS

JOURNAL OF AFFECTIVE DISORDERS | ELSEVIER SCIENCE BV | Published : 1982

Abstract

Platelet MAO activity and plasma thiocyanate concentrations were determined in 72 normal volunteers (22 non-smokers and 50 smokers). Thiocyanate concentrations were used as an index of exposure to cigarette smoke. A significant negative correlation between MAO and thiocyanate concentration was observed for the group (rs = 0.35; P less than 0.005). When examined by sex, the correlation was significant for females but not for males. Mean MAO activity was significantly lower for female smokers than for female non-smokers. For males, no significant differences in MAO activity were observed between smokers and non-smokers. It is possible that smoking causes inhibition of MAO by a direct effect or..

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