The regulation of cytokine signaling by SOCS proteins
CJ Greenhalgh, DJ Hilton
IMMUNOLOGIST | HOGREFE & HUBER PUBLISHERS | Published : 2000
A novel family of proteins that suppress cytokine signaling (SCOS) have recently been described. Here, Christopher L. Greenhalgh and Douglas J. Hilton provide an update on these, including the effects of gene knockouts or of overexpression, which indicate a role for them in a wide range of systems.