Multicentre evaluation of mianserin in depressive illness

Abstract

A multicentre evaluation of the effectiveness of mianserin in depressive illness was carried out. A total of 130 patients were treated with the drug, but useful data were collected on 55 patients; of these 36 responded to mianserin. A number of unwanted side effects were recorded. They were generally of mild to moderate severity, but occasionally were severe enough to warrant withdrawal of mianserin therapy. Mianserin was considered to be an effective antidepressent.