Effect of acute changes in sacral nerve stimulation amplitude on anorectal function in faecal incontinence.
AJ Malouf, MA Kamm, RJ Nicholls
Colorectal Dis | Published : 2000
OBJECTIVE: Sacral nerve stimulation improves faecal continence. Preliminary evidence suggests that the effect may be mediated via altered rectal and anal smooth muscle activity, as well as facilitation of external sphincter contraction. Clinical benefit however, appears unrelated to whether stimulation amplitude is above or below that required to produce threshold perineal sensation. Formal evaluation of the effect of different levels of stimulation has not been undertaken. This study aimed to assess the effect of varying stimulation amplitude on pelvic floor motor and sensory function in patients permanently implanted for faecal incontinence. PATIENTS AND METHODS: Three female patients with..View full abstract