Journal article

Preventing acute gout when starting allopurinol therapy. Colchicine or NSAIDs?

TV Kot, RO Day, PM Brooks

Medical Journal of Australia | Published : 1993

Abstract

Acute gout is a well known complication of the commencement of allopurinol therapy. Prophylaxis is needed for some months, even after serum urate levels have returned to normal. Colchicine is usually preferable to NSAIDs for this purpose, being cheaper, and better tolerated, especially in patients with peptic ulcer, gastrointestinal bleeding or dyspepsia or who are taking anticoagulants.