Design of bio-inspired fault-tolerant adaptive routing based on enzymatic feedback control in the cell: Towards averaging load balance in the network

Abstract

The routing algorithm of SPF is widely distributed in the Internet. Since this routing algorithm is designed in order to improve throughput of each packet, it is not suitable for averaging load balance in the network. On the contrary, metabolic networks in the cell can realize load balance and achieve fault-tolerance by using enzymatic feedback mechanism. That is, a metabolic pathway in the cell is composed of a lot of enzymatic reaction steps in which biochemical reactant (substrate) is converted to the product by unique enzyme, and the product of a late step frequently acts as an inhibitor of the first committed step in this pathway (feedback control). This way, the end product of a pathwa..