Conference Proceedings
Micro-injection system for localized drug delivery using embedded solid chemical propellant
Jae-won Ban, Kyo-in Koo, Sunkil Park, Gilsub Kim, Dong-il Dan Cho, D Howard (ed.), PK Rhee (ed.), S Halgamuge (ed.), SJ Yoo (ed.)
PROCEEDINGS OF THE FRONTIERS IN THE CONVERGENCE OF BIOSCIENCE AND INFORMATION TECHNOLOGIES | IEEE COMPUTER SOC | Published : 2007
Abstract
This paper presents a novel micro-injection system for localized drug delivery using embedded solid chemical propellant, azobisisobutyronitrile (AIBN). This system consists of in-plane type of microneedles, a drug reservoir, a chemical fluid source, a chemical fluid source chamber, and a microheater. The AIBN decomposes and produces nitrogen gas and a free radical at about 70 °C. Using this phenomenon, the AIBN on the microheater generates nitrogen gas by supplying an electrical power, and then the generated nitrogen gas injects a drug in the drug reservoir through the micro channel buried at the microneedles. This micro-injection system injects $2.29\sim 2.9\mu l$ blue ink during ab..
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