Description and Validation of High-Throughput Simultaneous Genotyping and Mutation Scanning by High-Resolution Melting Curve Analysis

Grants

Funding Acknowledgements

We thank the many families who have contributed to the Breast Cancer Family registries (BCFR) and Kathleen Cuningham Foundation Consortium for research into Familial Breast cancer (kConFab). We also thank Heather Thorne, Eveline Niederinayr, all the kConFab research nurses and staff, the heads and staff of the Family Cancer Clinics, and the Clinical Follow Up Study (funded by NHMRC grants 145684, 288704, and 454508) for their contributions to this resource. T.N.-D. is the recipient of a fellowship from the Fondation de France and S.G. is the recipient of a fellowship from University of Pisa and a Special Training Award from IARC. The content of this manuscript does not necessarily reflect the views or policies of the NCI or any of the collaborating centers in the CFR, nor does mention of trade names, commercial products, or organizations imply endorsement by the U.S. Government or the CFR. This work was supported by the National Cancer Institute, National Institutes of Health Wider RFA-CA-06-503 and R01-CA121245-01A2, and through cooperative agrements with members of the Breast Cancer Family Registry and P.I.s, Including Cancer Care Ontario (U01 CA69467), Northern California Cancer Center (U01 CA69417), and University of Melbourne (U01 CA69638). kConFab is supported by grants from the National Breast Cancer Foundation, the National Health and Medical Research Council (NHMRC), and by the Queensland Cancer Fund, the Cancer Councils Of New South Wales, Victoria, Tasmania, and South Australia, and the Cancer Foundation of Western Australia. Authored by members of the BCFR group: specifically Cancer Care Ontario, Fred A. Litwin Center for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada; the Northern California Cancer Center, Fremont, CA; and the Centre for Genetic Epidemiology, University of Melbourne, Carlton, Victoria, Australia; and members of thekConFab group: specifically the Peter MacCallum Cancer Centre, Melbourne, Australia.