Is Corneal Arcus Independently Associated With Incident Cardiovascular Disease in Asians?
Mark Yu Zheng Wong, Ryan Eyn Kidd Man, Preeti Gupta, Sing Hui Lim, Blanche Lim, Yih-Chung Tham, Charumathi Sabanayagam, Tien Yin Wong, Ching-Yu Cheng, Ecosse Luc Lamoureux
AMERICAN JOURNAL OF OPHTHALMOLOGY | ELSEVIER SCIENCE INC | Published : 2017
PURPOSE: To examine the longitudinal relationship between baseline corneal arcus (CA) and incident cardiovascular disease (CVD) in ethnic Indian and Malay adults in Singapore. DESIGN: Population-based cohort study. METHODS: Indian and Malay adults aged 40-80 years were recruited for baseline and 6-year follow-up visits between 2004-2009 and 2010-2015, respectively (follow-up response rate 73.9%). CA was assessed by ophthalmologists using slit-lamp biomicroscopy. The main outcome was self-reported incident CVD, defined as new myocardial infarction, angina pectoris, or stroke, which developed between baseline and follow-up. Multivariable logistic regression models assessed independent associat..View full abstract
Awarded by SINGAPORE MINISTRY OF HEALTH'S NATIONAL MEDICAL RESEARCH COUNCIL (NMRC) UNDER ITS TALENT Development Scheme
Awarded by Biomedical Research Council (BMRC), Singapore
SINGAPORE MINISTRY OF HEALTH'S NATIONAL MEDICAL RESEARCH COUNCIL (NMRC) UNDER ITS TALENT Development Scheme NMRC/STaR/0003/2008 and Biomedical Research Council (BMRC), Singapore 08/1/35/19/550.