Journal article

Longitudinal Associations of Serum 25-hydroxyvitamin D, Physical Activity, and Knee Pain and Dysfunction with Muscle Loss in Community-dwelling Older Adults

Saliu Balogun, Dawn Aitken, Tania Winzenberg, Karen Wills, David Scott, Michele Callisaya, Graeme Jones

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES | OXFORD UNIV PRESS INC | Published : 2018

Abstract

Aim: To describe the associations of between-person and within-person variability in serum 25-hydroxyvitamin D (25(OH)D), physical activity (PA), and knee pain and dysfunction with muscle mass, strength, and muscle quality over 10 years in community-dwelling older adults. Method: Participants (N = 1033; 51% women; mean age 63 ± 7.4 years) were measured at baseline, 2.5, 5, and 10 years. Lower limb lean mass (LLM) was assessed using dual energy X-ray absorptiometry, lower limb muscle strength (LMS) using a dynamometer, and lower limb muscle quality (LMQ) calculated as LMS/LLM. Knee pain and dysfunction were assessed using the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) in..

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University of Melbourne Researchers