Journal article
Incidence of sudden unexpected death in epilepsy in community-based cohort in China
Y Ge, D Ding, Q Zhang, B Yang, T Wang, B Li, J Wang, J Luo, P Kwan, W Wang, Z Hong, JW Sander
Epilepsy and Behavior | ACADEMIC PRESS INC ELSEVIER SCIENCE | Published : 2017
Abstract
Objective Sudden unexpected death in epilepsy (SUDEP) is associated with the high premature mortality observed among people with epilepsy. It is, however, considered a rare event in China, probably because of lack of awareness and limitation of studies in the country. We aimed to provide some initial estimation of the burden of SUDEP in China. Methods We established a large Chinese community-based cohort of people with epilepsy between January 2010 and December 2011. For any participant who died during follow-up, detailed information on cause of death was obtained using a specifically designed Verbal Autopsy Questionnaire. All cases were reviewed by a multidisciplinary expert panel and reinv..
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Awarded by National Institutes of Health
Funding Acknowledgements
We thank all the village physicians for their hard field work of follow-up, and all participants for their cooperation. JWS is based at UCLH/UCL Comprehensive Biomedical Research Centre, which receives a proportion of funding from the UK Department of Health's National Institute for Health Research Biomedical Research Centers funding scheme. He receives support from the Dr. Marvin Weil Epilepsy Research Fund and UK Epilepsy Society. This study was funded by National Natural Science Foundation of China (81271443), Key Research Project of the Chinese Ministry of Science and Technology (Grant No. 2016YFC0904400), and a NIH/NINDS grant (1R21NS069223-01).