Journal article
A very early rehabilitation trial after stroke (AVERT): a Phase III, multicentre, randomised controlled trial
P Langhorne, O Wu, H Rodgers, A Ashburn, J Bernhardt
Health Technology Assessment | NIHR JOURNALS LIBRARY | Published : 2017
DOI: 10.3310/hta21540
Abstract
Background: Mobilising patients early after stroke [early mobilisation (EM)] is thought to contribute to the beneficial effects of stroke unit care but it is poorly defined and lacks direct evidence of benefit. Objectives: We assessed the effectiveness of frequent higher dose very early mobilisation (VEM) after stroke. Design: We conducted a parallel-group, single-blind, prospective randomised controlled trial with blinded end-point assessment using a web-based computer-generated stratified randomisation. Setting: The trial took place in 56 acute stroke units in five countries. Participants: We included adult patients with a first or recurrent stroke who met physiological inclusion criteria...
View full abstractRelated Projects (1)
Grants
Awarded by National Institute for Health Research
Funding Acknowledgements
This project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 21, No. 54. See the NIHR Journals Library website for further project information. Funding was also received from the National Health and Medical Research Council Australia, Singapore Health, Chest Heart and Stroke Scotland, Northern Ireland Chest Heart and Stroke, and the Stroke Association. In addition, National Health and Medical Research Council fellowship funding was provided to Julie Bernhardt (1058635), who also received fellowship funding from the Australia Research Council (0991086) and the National Heart Foundation (G04M1571). The Florey Institute of Neuroscience and Mental Health, which hosted the trial, acknowledges the support received from the Victorian Government via the Operational Infrastructure Support Scheme.