Journal article

Interleukin-3 binding to the murine beta(IL-3) and human beta c receptors involves functional epitopes formed by domains 1 and 4 of different protein chains

JM Murphy, SC Ford, JE Olsen, SE Gustin, PD Jeffrey, DL Ollis, IG Young

Journal of Biological Chemistry | AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC | Published : 2004

DOI: 10.1074/jbc.M402705200

University of Melbourne Researchers

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Keywords

Alanine
Biochemistry & Molecular Biology
Mutation
Transfection
High-Affinity Binding
Cytokine Receptors
Crystal-Structure
Cross-Linking Reagents
Protein Binding
Mice
Mutagenesis, Site-Directed
Animals
Epitopes
Models, Molecular
Cell Division
Crystallography, X-Ray
Granulocyte-Macrophage Colony-Stimulating Factor
Humans
Ultracentrifugation
Il-5 Receptors
Kinetics
Life Sciences & Biomedicine
Protein Structure, Tertiary
Amino Acid Sequence
Cytokine Receptor Common Beta Subunit
Human Gm-Csf
Cos Cells
Receptors, Cell Surface
Dna, Complementary
Science & Technology
Human Growth-Hormone
Flow Cytometry
Dimerization
Molecular Sequence Data
Interleukin-5
Interleukin-3
Colony-Stimulating Factor
Sequence Homology, Amino Acid
Complete Extracellular Domain
Alpha-Chain
Expression Cloning
Cytokines
Electrophoresis, Polyacrylamide Gel