Journal article

Mutations in dihydropteroate synthase are responsible for sulfone and sulfonamide resistance in Plasmodium falciparum

T Triglia, JGT Menting, C Wilson, AF Cowman

Proceedings of the National Academy of Sciences | NATL ACAD SCIENCES | Published : 1997

DOI: 10.1073/pnas.94.25.13944

University of Melbourne Researchers

Alan Cowman Author Medical Biology (W.E.H.I.)

Tony Triglia Author Medical Biology (W.E.H.I.)

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Keywords

Science & Technology

Multidisciplinary Sciences

Drug Resistance

Plasmodium Falciparum

Hydroxymethyldihydropterin Pyrophosphokinase

Human Malaria Parasite

Escherichia Coli

Dihydropteroate Synthase

Antimalarial Activity

Science & Technology - Other Topics

Pyrimethamine Resistance

Multienzyme Complexes

Dihydrofolate-Reductase

Enzyme Inhibitors