A new mouse T-cell receptor alpha chain variable region family.
RM Sutherland, Y Paterson, PA Scherle, W Gerhard, AJ Caton
Immunogenetics | Published : 1991
Sequence analysis of the rearranged T-cell receptor alpha chain gene segments from an influenza reactive T-cell clone T2.5-5 and a hemin chloride reactive T-cell hybrid SJL-HE-1.1 have revealed a previously undescribed V alpha gene family. We have designated this family V alpha 15. Southern hybridization analysis has indicated that this family most probably contains only two members, and that these are conserved in each of six mouse strains representing three previously described V alpha haplotypes: V alpha a, V alpha b, and V alpha c.
Awarded by NIAID NIH HHS
Awarded by NIGMS NIH HHS