Voice Outcomes after Radiotherapy Treatment for Early Glottic Cancer: Long-Term Follow-Up

Abstract

OBJECTIVES: The aim of this study was to investigate long-term voice outcomes and voice-related quality of life (QOL) for early glottic cancer treated with radiotherapy. STUDY DESIGN: Long-term exploratory follow-up study of a prospective patient cohort comparing outcomes at a mean of 11 years postradiotherapy with the original 1-year posttreatment results. METHOD: Eight patients completed voice tasks for auditory perception and acoustic and aerodynamic measures. Patient-reported voice-related QOL (VR-QOL) and voice quality were measured. Changes in outcomes over time were analysed using repeated-measures linear mixed models. RESULTS: Acoustic and aerodynamic outcomes remained stable from 1 ..