Journal article
Inter-relationship between visual symptoms, activity limitation and psychological functioning in patients with diabetic retinopathy
EK Fenwick, GHL Cheng, REK Man, J Khadka, G Rees, TY Wong, K Pesudovs, EL Lamoureux
British Journal of Ophthalmology | BMJ PUBLISHING GROUP | Published : 2018
Abstract
Aims We explored the direct and indirect impact of restrictions in daily living activities on the relationship between perceived visual symptoms associated with diabetic retinopathy (DR) and psychological functioning. Methods In this prospective, cross-sectional study, 514 tertiary patients with DR (mean age±SD, 60.4±12.6 years; 64% male) answered questions related to nine domains of DR-specific quality of life. These were classified into the following predictor, mediating and outcome variables: visual symptoms (predictor variable); activity limitation, driving, lighting, social restriction, inconvenience, mobility (mediating variables); and emotional distress and concerns (outcome variables..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
This work was supported by National Health and Medical Research Council Centre for Clinical Research Excellence (CCRE) # 529923-Translational Clinical Research in Major Eye Diseases; CCRE Diabetes; Novartis Pharmaceuticals Australia #CRFB002DAU09T; Royal Victorian Eye and Ear Hospital; EKF was funded by the Australian National Health and Medical Research Council (NHMRC) Early Career Fellowship (#1072987). GR is funded by an NHMRC Career Development Award (#1061801) The Centre for Eye Research Australia receives Operational Infrastructure Support from the Victorian Government. The sponsor or funding organisation had no role in the design or conduct of this research.