Perioperative fluid management in major hepatic resection: an integrative review

Abstract

Background Fluid intervention and vasoactive pharmacological support during hepatic resection depend on the preference of the attending clinician, institutional resources, and practice culture. Evidence-based recommendations to guide perioperative fluid management are currently limited. Therefore, we provide a contemporary clinical integrative overview of the fundamental principles underpinning fluid intervention and hemodynamic optimization for adult patients undergoing major hepatic resection. Data sources A literature review was performed of MEDLINE, EMBASE and the Cochrane Central Registry of Controlled Trials using the terms “surgery”, “anesthesia”, “starch”, “hydroxyethyl starch deriva..