Journal article

Postoperative analgesia by continuous extradural infusion of ropivacaine after upper abdominal surgery.

SA Schug, DA Scott, J Payne, PH Mooney, B Hägglöf

British Journal of Anaesthesia | Published : 1996


Ropivacaine is a new local anaesthetic with advantages that suggest an important role in the provision of postoperative analgesia. The main aim of this study was to investigate the dose-response relationship of extradural infusion of ropivacaine. We studied 36 ASA I-III patients undergoing upper abdominal surgery during general anaesthesia and extradural block (catheter insertion at T6-9) using 0.5% ropivacaine in a randomized, double-blind study. After surgery nine patients each received an extradural infusion of either ropivacaine 0.1%, 0.2%, 0.3% or saline at a rate of 10 ml h-1 for 21 h. All patients had access to i.v. morphine via a PCA device. The ropivacaine groups consumed significan..

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University of Melbourne Researchers