Journal article

Development of a dynamic mathematical model for investigating mammary gland metabolism in lactating cows

V Volpe, JP Cant, RC Boston, P Susmel, P Moate

The Journal of Agricultural Science | Published : 2010


SUMMARYA dynamic mathematical model of a closed mammary system in lactating cows was developed to incorporate the setpoint concept of tissue activity, using equations where nutrient supply and absorption are locally regulated so as to maintain a given rate of milk protein yield. The model consists of 12 differential equations, 11 of which are concerned with intracellular biochemical compartments and one describes the volume of tissue actively perfused by blood (AP). The intracellular compartments are: amino acids (AAs), acetate, fatty acids (FAs), β-hydroxybutyrate, glucose-6-phosphate, fructose-6-phosphate, phospho-glyceraldehyde, pyruvate, mitochondrial acetyl-CoA, adenosine triphosphate (..

View full abstract

University of Melbourne Researchers

Citation metrics