Journal article

DISTRIBUTION OF ALPHA(2)-MACROGLOBULIN AND ALPHA(1)-ACID GLYCOPROTEIN MESSENGER-RNA SHOWS REGIONAL SPECIALIZATION IN RAT DECIDUA

T THOMAS

PLACENTA | W B SAUNDERS CO LTD | Published : 1993

Abstract

In situ hybridization histochemistry was used to detect mRNA coding for the plasma proteins alpha 1-acid glycoprotein and alpha 2-macroglobulin in the rat decidua during the period when the chorioallantoic placenta is established. It was found that alpha 1-acid glycoprotein mRNA was localized to a subpopulation of decidual cells predominantly found in the decidua capsularis but extending into the decidua basalis at later times. The highest levels of alpha 2-macroglobulin mRNA were found in the decidua basalis where there was some overlap with regions containing alpha 1-acid glycoprotein mRNA. No alpha 2-macroglobulin mRNA could be found in the inner part of the decidua capsularis where the h..

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University of Melbourne Researchers