Motor neurone disease: Progress and challenges

Abstract

Major progress has been made over the past decade in the understanding of motor neurone disease (MND), changing the landscape of this complex disease. Through identifying positive prognostic factors, new evidencebased standards of care have been established that improve patient survival, reduce burden of disease for patients and their carers, and enhance quality of life. These factors include early management of respiratory dysfunction with non-invasive ventilation, maintenance of weight and nutritional status, as well as instigation of amultidisciplinary teamincluding neurologists, general practitioners and allied health professionals. Advances in technology have enhanced our understanding ..