Journal article

Review: Placental derived biomarkers of pregnancy disorders.

James SM Cuffe, Olivia Holland, Carlos Salomon, Gregory E Rice, Anthony V Perkins

Placenta | Published : 2017


Pregnancy is one of the greatest physiological challenges that a women can experience. The physiological adaptations that accompany pregnancy may increase the risk of developing a number of disorders that can lead to both acute and chronic physiological outcomes. In addition, fetal development may be impaired and, if the fetus survives, the child may be at an increased risk of disease throughout life. Pregnancy disorders are poorly predicted by traditional risk factors and maternal history alone. The identification of biomarkers that can predict incidence and severity of disease would allow for improved and targeted prophylactic therapies to prevent adverse maternal and fetal outcomes. Many ..

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