Antisense oligonucleotide modified with serinol nucleic acid (SNA) induces exon skipping in: Mdx myotubes
BT Le, K Murayama, F Shabanpoor, H Asanuma, RN Veedu
RSC Advances | Published : 2017
We investigated the potential of SNA-modified antisense oligonucleotide (AO) for exon-skipping. We found that a 20-mer SNA-AO induced efficient exon-23 skipping in the mouse dystrophin gene transcript.