Postnatal changes in the cardiorespiratory response and ability to autoresuscitate from hypoxic and hypothermic exposure in mammals

Abstract

Most mammals are born immature and a great deal of maturational changes must occur early in the early postnatal life to prepare for life as an adult. In addition to the obvious changes such as physical and musculoskeletal growth, a myriad of physiological changes including the cardiorespiratory responses to hypoxia and hypothermia must also occur. The most intriguing developmental effect is perhaps the change in the ability to autoresuscitate, or spontaneous recovery from cardiorespiratory arrest induced by extreme hypoxia or hypothermia. For decades the ability of young animals to autoresuscitate from cardiorespiratory arrest induced by hypoxic or hypothermic exposure has been documented. I..