Journal article

Comparison of methods for fixed effect meta-regression of standardized differences of means

MJ Malloy, LA Prendergast, RG Staudte

Electronic Journal of Statistics | Published : 2011


Given a number of different studies estimating the same ef-fect size, it is often desired to explain heterogeneity of outcomes using concomitant covariates. For very large sample sizes, effect size estimates are approximately normally distributed and a straightforward application of weighted least squares is appropriate. However in practice within study sample variances are often small to moderate, casting doubt on the normal-ity assumption for effect sizes and results based on weighted least squares. One can alternatively variance stabilize the effect size estimates and adopt a generalized linear model. Both methods are compared on two examples when effect sizes are the standardized differe..

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