A Dynamic Stress Model Explains the Delayed Drug Effect in Artemisinin Treatment of Plasmodium falciparum
Pengxing Cao, Nectarios Klonis, Sophie Zaloumis, Con Dogovski, Stanley C Xie, Sompob Saralamba, Lisa J White, Freya JI Fowkes, Leann Tilley, Julie A Simpson, James M McCaw
Antimicrobial Agents and Chemotherapy | AMER SOC MICROBIOLOGY | Published : 2017
Awarded by National Health and Medical Research Centre of Australia (NHMRC)
Awarded by Centre for Research Excellence VicBioStat
Awarded by Centre for Research Excellence PRISM2
Awarded by Australian Research Council
The work was supported by the National Health and Medical Research Centre of Australia (NHMRC) through project grants 1100394 and 1060357, the Centre for Research Excellence VicBioStat (1035261), the Centre for Research Excellence PRISM<SUP>2</SUP> (1078068), and the Australian Research Council Discovery project (DP170103076). The Mahidol-Oxford Tropical Medicine Research Unit is supported by the Wellcome Trust of Great Britain. J.M.M. and F.F. were supported by Australian Research Council (ARC) Future Fellowships. L.T. was supported by an ARC Professorial Fellowship. J.A.S. was supported by an NHMRC Senior Research Fellowship.We acknowledge many useful conversations with David S. Khoury, Deborah Cromer, and Miles P. Davenport (Kirby Institute, UNSW, Australia), as well as Joel Tarning and Nicholas J. White (Mahidol University, Bangkok, Thailand). P.C. also thanks TDModNet for providing a traveling fellowship to enable collaboration on this project.