Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice
Jibran A Wali, Sandra Galic, Christina YR Tan, Esteban N Gurzov, Ann E Frazier, Timothy Connor, Jingjing Ge, Evan G Pappas, David Stroud, L Chitra Varanasi, Claudia Selck, Michael T Ryan, David R Thorburn, Bruce E Kemp, Balasubramanian Krishnamurthy, Thomas WH Kay, Sean L Mcgee, Helen E Thomas
Cell Death & Differentiation | NATURE PUBLISHING GROUP | Published : 2018
We thank Lorraine Elkerbout, Stacey Fynch, William Stanley, Jasmine McLeod, Lara Yachou-Wos, Sam Thorburn, Eva Orlowski (all St Vincent's Institute), Adrienne Laskowski (Murdoch Childrens Research Institute), Philippe Bouillet, Andreas Strasser, Lorraine O'Reilly, Marco Herold, Margs Brennan, David Huang, David Segal (The Walter and Eliza Hall Institute), Sara Ellis, Jill Danne and Chad Johnson (Peter MacCallum Cancer Centre), Greg Steinberg (McMaster University, Canada) and Sof Andrikopoulos (University of Melbourne) for experimental advice, technical assistance, reagents and critical reading of the manuscript. This work was funded by a National Health and Medical Research Council of Australia (NHMRC) Project grant, a NHMRC and Juvenile Diabetes Research Foundation joint special programme grant, and fellowships from the NHMRC. This work received support from the Operational Infrastructure Support Scheme of the Government of Victoria.