Journal article
Strongyloides stercoralis seroprevalence in Vietnam
NTN Diep, PQ Thai, NNM Trang, J Jäger, A Fox, P Horby, HVM Phuong, DD Anh, LTQ Mai, HR Van Doorn, B Nadjm
Epidemiology and Infection | CAMBRIDGE UNIV PRESS | Published : 2017
Open access
Abstract
Strongyloidiasis is a neglected tropical disease caused by the roundworm Strongyloides stercoralis affecting 30-100 million people worldwide. Many Southeast-Asian countries report a high prevalence of S. stercoralis infection, but there are little data from Vietnam. Here, we evaluated the seroprevalence of S. stercoralis related to geography, sex and age in Vietnam through serological testing of anonymized sera. Sera (n = 1710, 1340 adults and 270 children) from an anonymized age-stratified serum bank from four regions in Vietnam between 2012 and 2013 were tested using a commercial Strongyloides ratti immunoglobulin G ELISA. Seroreactivity was found in 29·1% (390/1340) of adults and 5·5% (15..
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Funding Acknowledgements
The study was funded by the Wellcome Trust through their Major Overseas Programme Grant to Vietnam. The funder had no role in the design, management, analysis or reporting of the study. The serum collection was approved by the Oxford Tropical Research Ethics Committee (OxTREC reference 27-12) and the Vietnamese Ministry of Health (reference 704/QD-BYT).