Strongyloides stercoralis seroprevalence in Vietnam
Thi Ngoc Diep Nguyen, Quang Thai Pham, Nguyen Minh Trang Nghiem, Julia Jaeger, Annette Fox, Peter Horby, Vu Mai Phuong Hoang, Duc Anh Dang, Thi Quynh Mai Le, H Rogier Van Doorn, Behzad Nadjm
EPIDEMIOLOGY AND INFECTION | CAMBRIDGE UNIV PRESS | Published : 2017
Strongyloidiasis is a neglected tropical disease caused by the roundworm Strongyloides stercoralis affecting 30-100 million people worldwide. Many Southeast-Asian countries report a high prevalence of S. stercoralis infection, but there are little data from Vietnam. Here, we evaluated the seroprevalence of S. stercoralis related to geography, sex and age in Vietnam through serological testing of anonymized sera. Sera (n = 1710, 1340 adults and 270 children) from an anonymized age-stratified serum bank from four regions in Vietnam between 2012 and 2013 were tested using a commercial Strongyloides ratti immunoglobulin G ELISA. Seroreactivity was found in 29·1% (390/1340) of adults and 5·5% (15..View full abstract
The study was funded by the Wellcome Trust through their Major Overseas Programme Grant to Vietnam. The funder had no role in the design, management, analysis or reporting of the study. The serum collection was approved by the Oxford Tropical Research Ethics Committee (OxTREC reference 27-12) and the Vietnamese Ministry of Health (reference 704/QD-BYT).