JAK2 phosphorylates histone H3Y41 and excludes HP1 alpha from chromatin

Grants

Funding Acknowledgements

We thank P. Flicek, S. Wilder, B. Huntly, S. J. Dawson and all the members of the A. R. G., B. G. and T. K. laboratories, in particular P. Hurd, B. Xhemalce, E. J. Baxter and P. Beer, for helpful discussions; A. Wood for sharing unpublished data; and J. LeQuesne for help with image analysis. This work was supported by PhD fellowship grants to M. A. D. from the General Sir John Monash Foundation, the Cambridge Commonwealth Trust and Raymond and Beverly Sackler. The Green ( A. R. G.) laboratory is funded by the UK Leukaemia Research Fund, the Wellcome Trust, the Leukemia & Lymphoma Society of America and the National Institute for Health Research Cambridge Biomedical Research Centre. The Gottgens ( B. G.) laboratory is funded by the Leukaemia Research Fund, Cancer Research UK, the Leukemia & Lymphoma Society of America and a Medical Research Council studentship to S. D. F. The Kouzarides ( T. K.) laboratory is funded by grants from Cancer Research UK and the 6th Research Framework Programme of the European Union ( Epitron, HEROIC and SMARTER).