Enantiospecific total synthesis of the squalene synthase inhibitors (-)-CJ-13,982 and its enantiomer from a common intermediate
Dayna Sturgess, Zongjia Chen, Jonathan M White, Mark A Rizzacasa
The Journal of Antibiotics | Springer Nature | Published : 2018
The total syntheses of both the natural and unnatural enantiomers of the alkyl citrate natural product CJ-13,982 (1) from the common D-ribose-derived acid 6 are described.
We thank Australian Research Council for funding.