Journal article

Impact of arch reobstruction and early hypertension on late hypertension after coarctation repair

MGY Lee, SL Allen, J Koleff, J Brink, IE Konstantinov, MMH Cheung, CP Brizard, Y d'Udekem

European Journal of Cardio Thoracic Surgery | OXFORD UNIV PRESS INC | Published : 2018

Abstract

OBJECTIVES: Late hypertension after coarctation repair is associated with high mortality, but its risk factors remain unclear. This study aims to determine early and late postoperative risk factors for late hypertension after coarctation repair. METHODS: A cross-sectional study including transthoracic echocardiogram and 24-h blood pressure (BP) monitoring was performed in 144 patients aged ≥10 years with previous coarctation repair. Median age at repair was 39 days (interquartile range 0-3 years). Early postoperative hypertension was evaluated by calculating the mean of BP measurements taken on the same day before hospital discharge or the need for antihypertensives prior to discharge. Multi..

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Grants

Awarded by National Health and Medical Research Council


Funding Acknowledgements

This work was supported by the Victorian Government's Operational Infrastructure Support Program and by a HeartKids Grant-in-Aid research grant. Melissa Lee was supported by a National Health and Medical Research Council (NHMRC) Medical Research Postgraduate Scholarship (1134274), a National Heart Foundation Health Professional Scholarship supported by The Noel and Imelda Foster Research Award (100681) and an Australian Government Research Training Program Scholarship. Yves d'Udekem is an NHMRC Clinician Practitioner Fellow (1082186).