Journal article

Electrophysiological Evidence of the Basilar-Membrane Travelling Wave and Frequency Place Coding of Sound in Cochlear Implant Recipients

Luke Campbell, Christofer Bester, Claire Iseli, David Sly, Adrian Dragovic, Anthony W Gummer, Stephen O'Leary



AIM: To obtain direct evidence for the cochlear travelling wave in humans by performing electrocochleography from within the cochlea in subjects implanted with an auditory prosthesis. BACKGROUND: Sound induces a travelling wave that propagates along the basilar membrane, exhibiting cochleotopic tuning with a frequency-dependent phase delay. To date, evoked potentials and psychophysical experiments have supported the presence of the travelling wave in humans, but direct measurements have not been made. METHODS: Electrical potentials in response to rarefaction and condensation acoustic tone bursts were recorded from multiple sites along the human cochlea, directly from a cochlear implant elect..

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Awarded by National Health and Medical Research Council (Australia)

Funding Acknowledgements

We thank the engineers from Cochlear Ltd. for assistance in developing software, the audiologists and staff at the Royal Victorian Eye and Ear Hospital Implant Clinic for their support during the project, the surgeons and surgical registrars of the Clinic, and Amy Hampson for proofreading. Luke Campbell was funded by the Garnett Passe and Rodney Williams Memorial Foundation. Stephen O'Leary was funded by the National Health and Medical Research Council (Australia), GNT0628679 and GNT1078673.