Journal article
Risk factors and pregnancy outcomes associated with placental malaria in a prospective cohort of Papua New Guinean women
E Lufele, A Umbers, J Ordi, M Ome-Kaius, R Wangnapi, H Unger, N Tarongka, P Siba, I Mueller, L Robinson, S Rogerson
Malaria Journal | Published : 2017
Abstract
METHODS: Placental biopsies were examined from 1451 pregnant women who were enrolled in a malaria prevention study at 14-26 weeks gestation. Clinical and demographic information were collected at first antenatal clinic visits and women were followed until delivery. Placental biopsies were collected and examined for PM using histology. The presence of infected erythrocytes and/or the malaria pigment in monocytes or fibrin was used to determine the type of placental infection.BACKGROUND: Plasmodium falciparum in pregnancy results in substantial poor health outcomes for both mother and child, particularly in young, primigravid mothers who are at greatest risk of placental malaria (PM) infection..
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Awarded by Bill and Melinda Gates Foundation
Funding Acknowledgements
This study was funded by the Malaria in Pregnancy Consortium, through a grant from the Bill & Melinda Gates Foundation (46099); the Pregvax Consortium, through a grant from the European Union's Seventh Framework Programme FP7-2007-HEALTH (PREGVAX 201588) and the Spanish Government (EUROSALUD 2008 Programme); and Pfizer Inc., through an investigator-initiated research grant (WS394663). LR was supported by an NHMRC Early Career Fellowship (# 1016443). The funders had no role in study design, data collection and analyses; decision to publish or preparation of the manuscript.