Solid-Phase Synthesis of Difficult Purine-Rich PNAs through Selective Hmb Incorporation: Application to the Total Synthesis of Cell Penetrating Peptide-PNAs

Julien Tailhades; Hotake Takizawa; Michael J Gait; Don A Wellings; John D Wade; Yoshitsugu Aoki; Fazel Shabanpoor

Journal article

Solid-Phase Synthesis of Difficult Purine-Rich PNAs through Selective Hmb Incorporation: Application to the Total Synthesis of Cell Penetrating Peptide-PNAs

Julien Tailhades, Hotake Takizawa, Michael J Gait, Don A Wellings, John D Wade, Yoshitsugu Aoki, Fazel Shabanpoor

Frontiers in Chemistry | FRONTIERS MEDIA SA | Published : 2017

DOI: 10.3389/fchem.2017.00081

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University of Melbourne Researchers

Fazel Shabanpoor Author Florey Department of Neuroscience and Mental Health

John Wade Author Florey Department of Neuroscience and Mental Health

Related Projects (1)

PEPTIDE CONJUGATES OF SPLICE-CORRECTING OLIGONUCLEOTIDES FOR ENHANCED CELL AND IN VIVO DELIVERY FOR THERAPY OF NEUROMUSCULAR DISEASES

Currently, there is no known cure for certain neuromuscular genetic disorders. However, recently identified synthetic DNA-type biomolecules ..

Grants

Awarded by CJ Martin Fellowship from the Australian National Health and Medical Research Council

Awarded by Bethlehem Griffith Research Foundation

Awarded by Medical Research Council (MRC programme)

Awarded by Medical Research Council

Funding Acknowledgements

FS is a recipient of a CJ Martin Fellowship (1034300) from the Australian National Health and Medical Research Council. JW is an NHMRC Principal Research Fellow (1117483). Work in the laboratory of FS was supported by the Bethlehem Griffith Research Foundation grant (BGRF1501). Work in the laboratory of MG was supported by the Medical Research Council (MRC programme number U105178803). We also acknowledge financial support from SpheriTech Ltd. (UK).