Journal article

Macro- and Microvascular Parameters After Toxic Shock Syndrome

Katherine YH Chen, Ling-Jun Li, Tien Y Wong, Carol Y Cheung, Nigel Curtis, Michael Cheung, David P Burgner

The Pediatric Infectious Disease Journal | LIPPINCOTT WILLIAMS & WILKINS | Published : 2018


Whether individuals who had toxic shock syndrome in childhood have differences in macro- and retinal microvascular parameters indicative of increased cardiovascular risk is unknown. We found no evidence of adverse macrovascular changes in 22 toxic shock syndrome participants compared with 60 control participants. Microvascular comparisons showed a reduction in retinal total fractal dimension, which has been associated with cardiovascular risk factors in children.


Awarded by National Health and Medical Research Council (NHMRC)

Awarded by National Heart Foundation Future Leader Fellowship

Awarded by NHMRC

Funding Acknowledgements

K.Y.H.C. holds an Australian Government Research Training Program scholarship from The University of Melbourne and a Postgraduate Health Research Scholarship from Murdoch Children's Research Institute. D.P.B. holds a National Health and Medical Research Council (NHMRC) Senior Research Fellowship (APP1064629) and an honorary National Heart Foundation Future Leader Fellowship (100369). N.C. is an investigator on NHMRC project grant 1064408. Research at Murdoch Children's Research Institute is supported by the Victorian Government's Operational Infrastructure Support Program. The Heart Research Group is supported by The RCH1000, The Royal Children's Hospital Foundation and Big W. The sponsors had no involvement in the study design, collection, analysis, interpretation and in the writing of this article.