Journal article

Risk of colorectal cancer for carriers of a germ-line mutation in POLE or POLD1

Daniel D Buchanan, Jenna R Stewart, Mark Clendenning, Christophe Rosty, Khalid Mahmood, Bernard J Pope, Mark A Jenkins, John L Hopper, Melissa C Southey, Finlay A Macrae, Ingrid M Winship, Aung Ko Win

Genet Med | NATURE PUBLISHING GROUP | Published : 2018


Awarded by National Cancer Institute

Awarded by Australasian Colorectal Cancer Family Registry

Funding Acknowledgements

This work was supported by grant UM1 CA167551 from the National Cancer Institute and through cooperative agreements with Australasian Colorectal Cancer Family Registry (U01 CA074778 and U01/U24 CA097735) and was conducted under Colon-CFR approval C-AU-0312-01. A.K.W. is an Australian National Health and Medical Council (NHMRC) Early Career Fellow. J.L.H. is an NHMRC Senior Principal Research Fellow and Distinguished Visiting Professor at Seoul National University, Korea. M.C.S. and M.A.J. are NHMRC Senior Research Fellows. C.R. is the Jass Pathology Fellow. D.D.B. is a University of Melbourne Research at Melbourne Accelerator Program (R@MAP) Senior Research Fellow and NHMRC R.D. Wright Career Development Fellow. The authors thank Susan Preston and Neil O'Callaghan from the Colorectal Oncogenomics Group and staff from the Genetic Epidemiology Laboratory for their contributions to this project. The authors thank all study participants of the Australasian Colorectal Cancer Family Registry and staff for their contributions to this project, in particular, Judi Maskiell, Maggie Angelakos, and Allyson Templeton.