Journal article
How convincing is a matching Y-chromosome profile?
MM Andersen, DJ Balding
Plos Genetics | PUBLIC LIBRARY SCIENCE | Published : 2017
Open access
Abstract
The introduction of forensic autosomal DNA profiles was controversial, but the problems were successfully addressed, and DNA profiling has gone on to revolutionise forensic science. Y-chromosome profiles are valuable when there is a mixture of male-source and female-source DNA, and interest centres on the identity of the male source(s) of the DNA. The problem of evaluating evidential weight is even more challenging for Y profiles than for autosomal profiles. Numerous approaches have been proposed, but they fail to deal adequately with the fact that men with matching Y-profiles are related in extended patrilineal clans, many of which may not be represented in available databases. The higher m..
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Awarded by Engineering and Physical Sciences Research Council
Funding Acknowledgements
The authors wish to thank the Isaac Newton Institute for Mathematical Sciences, Cambridge UK, for support and hospitality during the programme Probability and Statistics in Forensic Science, where this paper was conceived. The programme was supported by EPSRC grant no EP/K032208/1. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.