Journal article

Impact of Lactobacillus reuteri colonization on gut microbiota, inflammation, and crying time in infant colic

Monica L Nation, Eileen M Dunne, Shayne J Joseph, Fiona K Mensah, Valerie Sung, Catherine Satzke, Mimi LK Tang

Scientific Reports | NATURE PUBLISHING GROUP | Published : 2017


Awarded by Australian National Health and Medical Research Council (NHMRC)

Awarded by NHMRC ECF

Funding Acknowledgements

The Baby Biotics clinical trial was supported by the Georgina Menzies Maconachie Charitable Trust administered by Equity Trustees. VS (Postgraduate Scholarship 607447) and FM (ECF: 1037449, CDF: 1111160) have support from the Australian National Health and Medical Research Council (NHMRC) for the submitted work. VS is supported by a NHMRC ECF (1125687), a Royal Australasian College of Physicians Cottrell Research Establishment Fellowship, and has been supported by a Melbourne Children's Clinician Scientist Fellowship. CS holds an Australian NHMRC CDF: 1087957. BioGaia Sweden supplied the investigational product and placebo at no cost. Calpro AS supplied CalproLab ELISA kits for the analysis of calprotectin levels at no cost. BioGaia, Calpro AS, and Equitee Trustees were independent of the trial and its researchers and played no role in the trial design; in the collection, analysis, and interpretation of data; in the writing of the report; and in the decision to submit the article for publication. MT is an inventor on a patent owned by the Murdoch Children's Research Institute "A method of inducing tolerance", and is an employee of and holds share interest in ProTA. MT is a member of medical advisory board for Nestle Nutrition Institute, past member of Global Scientific Advisory Board for Danone Nutricia, received honoraria for presentations at symposia sponsored by Danone Nutricia, received probiotic and placebo research products from Nestle Research Centre Switzerland and Dicofarm Italy for studies unrelated to this trial. CS and ED received probiotic strains from Blis Technologies for studies unrelated to this trial. Murdoch Children's Research Institute is supported by the Victorian Government's Operational Infrastructure Support Program. The other authors have indicated they have no financial relationships relevant to this article to disclose.