Combining biological and psychosocial baseline variables did not improve prediction of outcome of a very-low-energy diet in a clinic referral population
P Sumithran, K Purcell, S Kuyruk, J Proietto, LA Prendergast
CLINICAL OBESITY | WILEY | Published : 2018
Consistent, strong predictors of obesity treatment outcomes have not been identified. It has been suggested that broadening the range of predictor variables examined may be valuable. We explored methods to predict outcomes of a very-low-energy diet (VLED)-based programme in a clinically comparable setting, using a wide array of pre-intervention biological and psychosocial participant data. A total of 61 women and 39 men (mean ± standard deviation [SD] body mass index: 39.8 ± 7.3 kg/m2 ) underwent an 8-week VLED and 12-month follow-up. At baseline, participants underwent a blood test and assessment of psychological, social and behavioural factors previously associated with treatment outcomes...View full abstract
LAP, PS and JP conceived the study; PS, KP and SK carried out the study; PS and LAP analysed data; all authors were involved in writing the paper and had final approval of the submitted version. We thank Dr. Mark Ng Tang Fui, Dr. Aye Nyein Tint, Dr. Sarah Price, Jodie Prendergast, Lisa Walker and Fraser Tull for their assistance with the study. This work was supported by a grant from the Bupa Health Foundation.